DIALIGN: multiple DNA and protein sequence alignment at BiBiServ
نویسندگان
چکیده
منابع مشابه
DIALIGN: multiple DNA and protein sequence alignment at BiBiServ
DIALIGN is a widely used software tool for multiple DNA and protein sequence alignment. The program combines local and global alignment features and can therefore be applied to sequence data that cannot be correctly aligned by more traditional approaches. DIALIGN is available online through Bielefeld Bioinformatics Server (BiBiServ). The downloadable version of the program offers several new pr...
متن کاملDIALIGN: finding local similarities by multiple sequence alignment
MOTIVATION DIALIGN is a new method for pairwise as well as multiple alignment of nucleic acid and protein sequences. While standard alignment programs rely on comparing single residues and imposing gap penalties, DIALIGN constructs alignments by comparing whole segments of the sequences. No gap penalty is employed. This point of view is especially adequate if sequences are not globally related,...
متن کاملDIALIGN at GOBICS—multiple sequence alignment using various sources of external information
DIALIGN is an established tool for multiple sequence alignment that is particularly useful to detect local homologies in sequences with low overall similarity. In recent years, various versions of the program have been developed, some of which are fully automated, whereas others are able to accept user-specified external information. In this article, we review some versions of the program that ...
متن کاملDIALIGN-TX and multiple protein alignment using secondary structure information at GOBICS
We introduce web interfaces for two recent extensions of the multiple-alignment program DIALIGN. DIALIGN-TX combines the greedy heuristic previously used in DIALIGN with a more traditional 'progressive' approach for improved performance on locally and globally related sequence sets. In addition, we offer a version of DIALIGN that uses predicted protein secondary structures together with primary...
متن کاملProtein multiple sequence alignment.
Protein sequence alignment is the task of identifying evolutionarily or structurally related positions in a collection of amino acid sequences. Although the protein alignment problem has been studied for several decades, many recent studies have demonstrated considerable progress in improving the accuracy or scalability of multiple and pairwise alignment tools, or in expanding the scope of task...
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ژورنال
عنوان ژورنال: Nucleic Acids Research
سال: 2004
ISSN: 0305-1048,1362-4962
DOI: 10.1093/nar/gkh373